Oral Tablet -> Thyromix


Thyromix

Pharmaceutical Name: Thyromix

Chemical Name: Liothyronine Sodium (T3), Levothyroxine sodium (T4)

Unit Available:100 Tabs

Each tablet contain: 80 mcg.

Description


Levothyroxine sodium is a synthetically manufactured form of the natural thyroid hormone tetraiodothyronine (T-4). Thyroid hormones are primarily responsible for regulating the body’s metabolic rate, and play a vital role in the body’s utilization of protein, fat, and carbohydrates. Levothyroxine sodium is used medically to treat cases of hypothyroidism, which is characterized by insufficient natural production of thyroid hormones.This may manifest itself with a number of symptoms including loss of energy, lethargy, weight gain, hair loss, and changes in skin texture. Levothyroxine sodium is considered a slow-acting medication, and may take up to 4 to 6 weeks before full therapeutic levels are reached in the blood. It is also the most commonly prescribed thyroid medication in the world, and is considered to be the standard form of treatment for most cases of hypothyroidism.

The action of levothyroxine sodium is very similar to that of the popular thyroid preparation Lionine -T3 (liothyronine sodium). Lionine -T3 is slightly different in structure, however, being a synthetic form of the thyroid hormone triiodothyronine (T-3). A healthy individual with have sufficient levels of both T-3 and T-4 thyroid hormones present in their body. T-3 is considered the primary active form of thyroid hormone, while T4 serves mainly as a reserve for T3, exerting most of its metabolic activity via conversion to T3 in peripheral tissues. T3 is regarded as having an effect that is roughly four times stronger than that of T-4 on a milligram-for-miIIigram basis. Likewise, Lionine -T3 is considered to be a more potent form of thyroid medication, both with regard to activity and side effect potential.

Levothyroxine sodium is valued by many drug-using athletes and bodybuilders for its ability to stimulate the metabolic rate and support the breakdown of body fat stores. It is usually taken during a period of calorie restriction (”cutting"), when the individual is focused on fat loss or increasing muscle definition. It is often thought that the use of thyroid drugs can support fat loss at a higher level of caloric intake than would otherwise be possible without the drugs, adding to their perceived value among the communities. Anabolic steroids are generally used in conjunction with these hormones, and many believe that the metabolism boosting effect of these drugs may Produce faster gains in muscle mass. The drugs, however, have yet to be widely proven or accepted for this purpose.

 

Structural Characteristics

 

Levothyroxine sodium is a synthetic form of T4 thyroid hormone. lt has the chemical designation L-3,3' ,5,5'- tetraiodothyronine sodium salt.

 


Dosage Recommanded

 

When used to treat mild to moderate hypothyroidism, the average replacement dose of levothyroxine sodium is approximately 1.7 mcg/kg/day. This equates to 100-125 mcg/day per day for a 154lb adult. The full therapeutic dose may be given from the onset of therapy in otherwise healthy adult patients. Note that due to the long half-life of levothyroxine, the peak therapeutic effect at a given dose may not be achieved for 4 to 6 weeks.

When used (off-label) to accelerate fat loss by bodybuilders and athletes, the typical protocol involves slow buildup of the dosage so that the body has ample time to adjust to the changing thyroid hormone levels. An individual will generally start with a low dosage of 25-50 mcg, and will slowly increase the amount 25-50 mcg each day or two.The final dosage will usually be in the range of 100-150 mcg, and will rarely exceed 250 mcg. It is important to remember that thyroid drugs are strong  medications with significant side effect potential. Cautious individuals will be sure not to use excessive amounts of levothyroxine sodium, nor continue treatment for longer than eight weeks. It is also generally advised to also reduce the Synthroid dosage gradually at the conclusion of each cycle. This is usually accomplished by dropping the dosage by 25 mcg every second or third day. The focus here, again, is to help avoid any sudden change in hormone levels that might otherwise trigger side effects. Note that due to the slow acting nature of levothyroxine sodium, it may take several weeks or longer for the active drug to be fully eliminated from the body.

 

Side Effects

 

Side effects are generally associated with overdosage, and may include headache, irritability, nervousness, sweating, irregular heartbeat, increased bowel motility, or menstrual irregularities. Overdosage may also induce shock,and may aggravate or trigger angina or congestive heart failure. Chronic overexposure to levothyroxine sodium will produce symptoms normally associated with hyperthyroidism, or the overproduction of natural thyroid hormones rn the body. The occurrence of verexposure-lrnked side effects rs normally cause to immediately reduce or discontinue therapy with levothyroxine sodium. Acute massive overdose may be life threatening.



 

Systematic name : (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid